Brand Name : Oryzogen
Model Number : HY100M1
Certification : ISO 9001 certificate
Place of Origin : China
MOQ : Negotiation
Price : Negotiation
Payment Terms : T/T
Supply Ability : 1000kg
Delivery Time : 3~5 days
Packaging Details : 1g/vial 10g/vial 50g/vial
Source : Rice Grain (Oryza Sativa)
Molecular weight : 66.5kD
Physical Appearance : Off-white to light beige lyophilized powder
Amino acid sequence : Same with HSA from plasma
CAS No. : 70024-90-7
Formulation : Lyophilized powder
Quick Details
1. CAS No.: 70024-90-7
2. Other Names: rHSA, recombinant HAS, RecHSA, Recombinant Albumin
3. Purity: Greater than 99 % as determined by SDS-PAGE
4. Source: Rice Grain (Oryza Sativa)
5. Formulation: rHSA is lyophilized with saline
6. Physical Appearance: Off-white to light beige lyophilized powder
Description
Human serum albumin is the most abundant protein in human plasma. It can transport hormones, lipds and other molecules and maintain osmotic pressure. Healthgen Biotech has developed the rice endosperm cell expression platform (OryzHiExp), which has such advantages: high expression level, safety, scale-up easily, simple production process and environmental protection etc. Animal free rHSA is a recombinant human serum derived from rice grains, and doesn't contain any animal component, which is much safer than plasma derived HSA.
Healthgen Biotechnology Corp. has been committed in research of protein purification, meanwhile our technology has been patented by the US Patent and Trademark Office on May 15th 2015 and been granted the patent of "A method for isolating and purifying recombinant human serum albumin from transgenic rice grain", which patent number is US9, 023,990. Now, our rHSA purity can be as high as 99%.
Human serum albumin is derived from human plasma, which is collected from different human bodies. So we cannot guarantee the stability of human serum albumin from different batches. Because of this, it is difficult to apply to large-scale application in vaccine production and cell culture. However, Healthgen uses State-of-the-art platform, having high capacity to express proteins and peptides in the rice grain. The platform uses rice endosperm cells as a bioreactor to specifically and highly express various recombinant proteins and small peptides. By using homozygous rice as the raw material, with the world's top production process, Healthgen can maximize the stability of albumin batches to meet the needs of industrial production.
Physiological and Biochemical Properties of rHSA and pHSA
Char. | pHSA | rHSA |
Amino Acids Sequence | Same | Same |
N-terminus | DAHKSEV | DAHKSEV |
C-terminus | KLVAASQAALGL | KLVAASQAALGL |
Glycosylation | No | No |
Molecular Mass(MALDI) | 66.554KD | 66.550KD |
PI | 4.8 | 4.8 |
Crystal Structure | Identical | Identical |
Supplemental Description
Healthgen quality control system has been certified by ISO 9001:2008 and ensure standardized process as well as qualified products.
Healthgen has a professional quality control department, in which 50% of them have master's degree or higher. There are 14 employees in the quality department, 9 of them are in QA and 5 are in QA. All of them have rich experience in analysis research or quality inspection. Every year there are more than 50 training courses, which cover GMP, SOP, specification, hygiene, QA, QC issues, etc.
We strictly control the quality of our products to ensure that all products into the market will be in line with quality standards.
Healthgen has a series of instruments, which are listed as below.
Equipment | Origin |
Microplate reader | Bio-Tek |
Osmotic pressure detector | Tianjin SMC30C-1 |
Liquid Chromatograph | Agilent |
Gas Chromatograph | PE |
Kjeldahl apparatus | Jinan K9840 |
RT-PCR | ABI |
Karl fischer moisture meter | Mettler Toledo |
Atomic absorption instrument | PE |
HY100M1 human serum protein , Recombinant Serum Albumin Light Beige Lyophilized Powder Images |
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